Litoxetine
Litoxetine is a dual-acting small molecule that selectively inhibits serotonin (5-HT) reuptake and antagonizes the 5-HT3 receptor. It exhibits antidepressant and antiemetic activities, as demonstrated by its dose-dependent reduction of vomiting in ferret models and its affinity for central 5-HT3 receptors (Ki = 85 nM) . This profile supports its research use in neuropharmacology and emesis studies.
Product Specifications
CAS Number
86811-09-8
Product Name Alternative
5-HT transporter, 5-HT3, 5HT Receptor, 5HTReceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.12% (May vary between batches)
Solubility
DMSO:10 mg/mL (41.44 mM)
Smiles
C (OC1CCNCC1) C2=CC3=C (C=C2) C=CC=C3
Molecular Formula
C16H19NO
Molecular Weight
241.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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