3-Hydroxykynurenamine
3-Hydroxykynurenamine (3-HKA) is an anti-inflammatory tryptophan metabolite that inhibits the IFN-γ/STAT1/NF-κB pathway in dendritic cells, reducing pro-inflammatory cytokines. It demonstrates protective effects in murine models of psoriasis and immune-mediated glomerulonephritis by ameliorating disease pathology and modulating T cell responses.
Product Specifications
CAS Number
99362-47-7
Field of Research
Immunology & Inflammation
Smiles
C (CCN) (=O) C1=C (N) C (O) =CC=C1
Molecular Formula
C9H12N2O2
Molecular Weight
180.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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