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3-Hydroxykynurenamine

3-Hydroxykynurenamine (3-HKA) is an anti-inflammatory tryptophan metabolite that inhibits the IFN-γ/STAT1/NF-κB pathway in dendritic cells, reducing pro-inflammatory cytokines. It demonstrates protective effects in murine models of psoriasis and immune-mediated glomerulonephritis by ameliorating disease pathology and modulating T cell responses.

Product Specifications

CAS Number

99362-47-7

Field of Research

Immunology & Inflammation

Smiles

C (CCN) (=O) C1=C (N) C (O) =CC=C1

Molecular Formula

C9H12N2O2

Molecular Weight

180.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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