BMS-214662 hydrochloride
BMS-214662 is a nonsedating benzodiazepine-derived farnesyltransferase inhibitor with antineoplastic potential. It blocks protein farnesylation, disrupting Ras-mediated signaling to induce apoptosis in tumor cells, including those with and without Ras mutations, as demonstrated in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
195981-08-9
Field of Research
Metabolism Research, Signal Transduction
Smiles
Cl.O=S (=O) (N1Cc2cc (ccc2N (Cc2c[nH]cn2) C[C@H]1Cc1ccccc1) C#N) c1cccs1
Molecular Formula
C25H24ClN5O2S2
Molecular Weight
526.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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