IRC-083927 HCl
IRC-083927 HCl is a novel colchicine-site microtubule polymerization inhibitor with potent in vitro anticancer activity in the low nanomolar range, including against taxane- and vinca-resistant cell lines. It demonstrates significant in vivo efficacy by orally inhibiting the growth of human cervical and breast cancer xenografts in mouse models, supporting its investigation for advanced, resistant cancers.
Product Specifications
CAS Number
955082-09-4
Smiles
Cl.NS (=O) (=O) Nc1ccc (Oc2ccc (cc2) -c2cnc (COc3ccccc3) [nH]2) cc1F
Molecular Formula
C22H19FN4O4S
Molecular Weight
454.47
Storage Conditions
-20°C
Notes
For research use only.
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