AEG40826
AEG40826 (HGS1029) is a small-molecule IAP inhibitor that antagonizes IAP proteins to restore caspase-mediated apoptosis, potentially overcoming chemoresistance. It is applied in oncology research, demonstrating synergistic antitumor activity with cytotoxic agents in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
949963-04-6
Smiles
C ([C@@H] (NC ([C@@H] (NC) C) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (N[C@H]2C=3C (CCC2) =CC=CC3) =O) C[C@H] (NC (=O) C4=CC=C (C (N[C@@H]5CN (C ([C@@H] (NC ([C@@H] (NC) C) =O) C (C) (C) C) =O) [C@H] (C (N[C@H]6C=7C (CCC6) =CC=CC7) =O) C5) =O) C=C4) C1
Molecular Formula
C58H80N10O8
Molecular Weight
1045.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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