Adriforant
Adriforant is a potent and selective competitive antagonist of the histamine H4 receptor. It inhibits histamine-driven ERK phosphorylation, calcium mobilization, and gene expression changes, demonstrating efficacy in reducing itch and inflammatory responses in murine models of skin inflammation.
Product Specifications
CAS Number
943057-12-3
Product Name Alternative
Adriforant, PF03893787, PF-03893787, PF 3893787, PF3893787, PF-3893787, PF 03893787, ZPL 389, ZPL 3893787, ZPL389, ZPL-389, ZPL3893787, ZPL3893797, ZPL-3893797
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.84% (May vary between batches)
Smiles
N (C) [C@H]1CN (CC1) C=2C=C (NCC3CC3) N=C (N) N2
Molecular Formula
C13H22N6
Molecular Weight
262.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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