Mal-Phe-C4-VC-PAB-MMAE
Product Specifications
UNSPSC Description
Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate.
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-phe-c4-vc-pab-mmae.html
Purity
99.54
Solubility
DMSO : 200 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC4=CC=C(N5C(C=CC5=O)=O)C=C4)=O)=O)=O)C=C3)=O)=O)=O)=O)OC)=O
Molecular Weight
1364.67
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126686/Mal-Phe-C4-VC-PAB-MMAE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126686/Mal-Phe-C4-VC-PAB-MMAE-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2259318-51-7
Available Sizes
Curated Selection
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