SB1578
SB1578 (ONX-0805) is an orally active, selective JAK2 inhibitor with additional potent activity against FLT3 and c-Fms. It effectively blocks downstream signaling, demonstrating high efficacy in rodent arthritis models, making it a valuable tool for researching autoimmune diseases and hematological malignancies in both in vitro and in vivo settings.
Product Specifications
CAS Number
937273-04-6
Smiles
O (CCN1CCCC1) C=2C3=CC (N=C4NC (C=5OC (=CC5) COC/C=C/COC3) =CC=N4) =CC2
Molecular Formula
C26H30N4O4
Molecular Weight
462.54
Storage Conditions
-20°C
Notes
For research use only.
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