TLS-IN-5
TLS-IN-5 (Rev1-IN-5) is a first-in-class small molecule inhibitor that selectively targets the Rev1 C-terminal domain (Rev1-CT) to disrupt translesion synthesis. This compound is a valuable chemical probe for investigating TLS mechanisms and their roles in cancer therapy resistance, both in cellular and biochemical studies.
Product Specifications
CAS Number
908510-73-6
Field of Research
Neuroscience
Smiles
C (NC1CC1) (=O) C=2C3=C (SC2NC (=O) C4CCN (C (C) =O) CC4) CC (C) CC3
Molecular Formula
C21H29N3O3S
Molecular Weight
403.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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