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AMG-1

AMG-1 is a selective CRAC channel inhibitor that suppresses effector T cell activity while sparing regulatory T cells in vitro. It has been shown to ameliorate disease progression in the EAE mouse model, making it a useful research tool for studying T cell-mediated autoimmunity and calcium signaling.

Product Specifications

CAS Number

903591-53-7

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

ClC=1C (=CC (C (F) (F) F) =CC1) C=2C=NC (NC (=O) C3=C (F) C=CC=C3F) =CN2

Molecular Formula

C18H9ClF5N3O

Molecular Weight

413.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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