ZK-Thiazolidinone
ZK-Thiazolidinone (TAL) is a potent and selective ATP-competitive inhibitor of PLK1 (IC50 = 19 nM) . It disrupts mitotic processes like centrosome maturation and spindle assembly in vitro, leading to prometaphase arrest in vivo, and inhibits proliferation in various human and mouse tumor cell lines.
Product Specifications
CAS Number
891849-87-9
Smiles
C (C (NCC (F) (F) F) =O) (C#N) =C1N (CC) C (=O) C (=CNC2=CC (CCN3CCCC3) =CC=C2) S1
Molecular Formula
C23H26F3N5O2S
Molecular Weight
493.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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