RO4927350
RO4927350 is a potent, selective non-ATP-competitive MEK1/2 inhibitor that suppresses MAPK signaling and demonstrates antitumor efficacy in diverse preclinical models. It uniquely inhibits basal and feedback-induced MEK phosphorylation, making it a valuable research tool for studying cancers driven by aberrant MAPK pathway activation in both cellular and animal studies.
Product Specifications
CAS Number
876755-27-0
Field of Research
Signal Transduction
Smiles
[C@H] ([C@@H] (C) C1=CC=CC=C1) (C (NC2=NC (C (CC) =O) =CS2) =O) N3C (=O) [C@H] (NC3=O) C4=CC=C (OCCO) C=C4
Molecular Formula
C27H28N4O6S
Molecular Weight
536.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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