BI-4834
BI-4834 is a potent and selective PLK1 inhibitor, an analogue of BI-2536, exhibiting an IC50 of 7.6 nM against PLK1 with improved selectivity over PLK3 (IC50 198.4 nM) . This compound is a valuable chemical probe for studying cell cycle regulation, mitosis, and oncology research in both cellular and preclinical models.
Product Specifications
CAS Number
876371-13-0
Smiles
C (C) (C) N1C=2C (N (C) C (=O) [C@H]1CC) =CN=C (NC3=C (OC) C=C (C (N[C@@H]4CC[C@H] (CC4) N5C[C@@H] (C) O[C@@H] (C) C5) =O) C=C3) N2
Molecular Formula
C32H47N7O4
Molecular Weight
593.76
Storage Conditions
-20°C
Notes
For research use only.
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