XL-418
XL-418 is an orally bioavailable small molecule inhibitor targeting AKT (PKB) and p70S6K, key kinases downstream of PI3K that are frequently overactive in cancers. Its dual inhibition promotes tumor cell apoptosis and suppresses protein translation, making it a valuable tool for investigating PI3K pathway biology in both cellular and animal models of oncology research.
Product Specifications
CAS Number
871343-09-8
Smiles
BrC=1C2=C (N=CN=C2NN1) N3CCN (CC3) C4=CC (C (CCC (F) (F) F) =O) =CC (NCCN5CCCC5) =C4C
Molecular Formula
C26H32BrF3N8O
Molecular Weight
609.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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