XL-418
XL-418 is an orally bioavailable small molecule inhibitor targeting AKT (PKB) and p70S6K, key kinases downstream of PI3K that are frequently overactive in cancers. Its dual inhibition promotes tumor cell apoptosis and suppresses protein translation, making it a valuable tool for investigating PI3K pathway biology in both cellular and animal models of oncology research.
Product Specifications
CAS Number
871343-09-8
Smiles
BrC=1C2=C (N=CN=C2NN1) N3CCN (CC3) C4=CC (C (CCC (F) (F) F) =O) =CC (NCCN5CCCC5) =C4C
Molecular Formula
C26H32BrF3N8O
Molecular Weight
609.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K6820208 1.0 µg DNA
Prkg1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
LV731358 1.0 µg DNA
LINC00342 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details