2-MT-63

2-MT 63 is a selective TIE-2 kinase inhibitor with a distinct profile, showing >30-fold selectivity against key angiogenic kinases like KDR, PDGFR, and EPHB4 in enzyme assays. It is a valuable research tool for studying TIE-2 signaling in angiogenesis and tumor microenvironment models, both in vitro and in vivo.