CEP-14083
CEP-14083 is a potent, ATP-competitive ALK inhibitor with an IC50 of 11 nM, also active against the insulin receptor. It modulates T-cell identity signaling via NPM/ALK inhibition and has demonstrated preclinical efficacy in both cellular assays and animal models of ALK-altered lymphoma.
Product Specifications
CAS Number
856692-39-2
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (CC) N1C=2C (=C3C (=C4C2CCC=5C4=CN (C) N5) C (=O) NC3) C=6C1=CC=C (NC (N (C) C7=CC=CC=C7) =O) C6
Molecular Formula
C31H30N6O2
Molecular Weight
518.61
Storage Conditions
-20°C
Notes
For research use only.
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