PF-00337210
PF-00337210 is an orally bioavailable, ATP-competitive inhibitor selectively targeting VEGFR2 tyrosine kinase. Its inhibition of VEGFR2 phosphorylation disrupts tumor angiogenesis, as demonstrated in in vitro endothelial cell assays and in vivo xenograft models, supporting its investigation as an antineoplastic agent.
Product Specifications
CAS Number
854514-88-8
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (NC) (=O) C=1C=2C (=CC (OC=3C4=C (C=C (OCCN5CCOCC5) C=C4) N=CC3) =CC2) OC1C
Molecular Formula
C26H27N3O5
Molecular Weight
461.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal Dynactin Subunit 2/DCTN2/DCTN-50 Antibody [DyLight 680]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-97257FR 0.1 mL
Rabbit Polyclonal Dynactin Subunit 2/DCTN2/DCTN-50 Antibody [DyLight 680]
Sign In for Pricing
View Details GTR15116267 1 Vial
Lentiviral human C22orf23 shRNA (UAS) - Lentiviral human C22orf23 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details bs-8127R-PerCP-Cy5.5 100 µL
CCDC28A Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Sign In for Pricing
View Details 
K7532105 3x 1.0 µg
Gcdh sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details