FTR-1335
FTR1335 is a potent and selective fungal N-myristoyltransferase (NMT) inhibitor (IC50 = 0.49 nM) . It exhibits fungicidal activity, including against fluconazole-resistant Candida strains, by blocking protein myristoylation. This compound is a valuable tool for investigating antifungal mechanisms in both in vitro and in vivo research models.
Product Specifications
CAS Number
851075-79-1
Smiles
N (C (=O) C1CCCC1) C=2SC=3C (N2) =CC=C (NC (=O) [C@H]4C[C@@H] (NCC5=CC6=C (C=C5) C=CC=C6) CCC4) C3
Molecular Formula
C31H34N4O2S
Molecular Weight
526.69
Storage Conditions
-20°C
Notes
For research use only.
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