TPI-287
TPI 287 is a third-generation synthetic taxane and antineoplastic agent that functions by binding to and stabilizing tubulin, thereby disrupting microtubule dynamics. This action induces G2/M cell cycle arrest and apoptosis, and it has been investigated in preclinical in vitro and in vivo studies for cancers including treatment-resistant tumors.
Product Specifications
CAS Number
849213-15-6
Field of Research
Metabolism Research, Signal Transduction
Smiles
O (C (C) =O) [C@]12[C@@]3 ([C@]4 (C) [C@] ([C@@H] (OC (C) =O) C=5C (C) (C) [C@] (O) ([C@H]3OC (=O) C6=CC=CC=C6) C[C@H] (OC ([C@@H] ([C@@H] (NC (OC (C) (C) C) =O) CC (C) C) O) =O) C5C) (OC (C=C) O[C@]4 (C[C@]1 (OC2) [H]) [H]) [H]) [H]
Molecular Formula
C46H63NO15
Molecular Weight
869.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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