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ICG acid

ICG acid is a fluorescent dye used in medical diagnostics. ICG acid has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue. ICG acid has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors[1][2].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/icg-acid.html

Solubility

10 mM in DMSO

Smiles

FC(F)(C([O-])=O)F.O=S(CCCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCCCC(O)=O)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56)(O)=O

Molecular Formula

C46H49F3N2O7S

Molecular Weight

830.95

References & Citations

[1]Taylor JS, et al. Combined application of Indocyanine green (ICG) and laser lead to targeted tumor cell destruction. J Pediatr Surg. 2018;53 (12) :2475-2479.|[2]Mačianskienė R, et al. Spectral characteristics of voltage-sensitive indocyanine green fluorescence in the heart. Sci Rep. 2017;7 (1) :7983. Published 2017 Aug 11.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Curated Selection

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