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GPI-15427

GPI-15427 is a brain-penetrant, nanomolar-potency PARP-1 inhibitor. It enhances the efficacy of temozolomide and radiotherapy in CNS tumors and HNSCC, as demonstrated in preclinical in vitro and in vivo studies for glioblastoma and lymphoma research.

Product Specifications

CAS Number

805242-85-7

Field of Research

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Smiles

O=C1C2=C3C (C=4C (OC3=CC=C2) =CC=C (CN5CCN (C) CC5) C4) =NN1

Molecular Formula

C20H20N4O2

Molecular Weight

348.4

Storage Conditions

-20°C

Notes

For research use only.

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