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KU-0058948

KU-0058948 is a potent and selective PARP inhibitor. It has been shown to induce cell cycle arrest and apoptosis in primary myeloid leukemic cells and established leukemic cell lines in vitro. Its mechanism supports research in oncology, particularly for studying DNA damage response and potential therapeutic strategies in hematological malignancies.

Product Specifications

CAS Number

763111-49-5

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

C (C=1C=2C (C (=O) NN1) =CC=CC2) C3=CC (C (=O) N4CCCNCC4) =C (F) C=C3

Molecular Formula

C21H21FN4O2

Molecular Weight

380.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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