KU-0058948
KU-0058948 is a potent and selective PARP inhibitor. It has been shown to induce cell cycle arrest and apoptosis in primary myeloid leukemic cells and established leukemic cell lines in vitro. Its mechanism supports research in oncology, particularly for studying DNA damage response and potential therapeutic strategies in hematological malignancies.
Product Specifications
CAS Number
763111-49-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (C=1C=2C (C (=O) NN1) =CC=CC2) C3=CC (C (=O) N4CCCNCC4) =C (F) C=C3
Molecular Formula
C21H21FN4O2
Molecular Weight
380.42
Storage Conditions
-20°C
Notes
For research use only.
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