Puupehenone
Puupehenone is a natural Hsp90 inhibitor that restores caspofungin efficacy against resistant fungi. It functions by blocking the cell wall integrity pathway, preventing the transcriptional adaptation to echinocandin stress. This compound is a valuable research tool for studying antifungal resistance mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
73573-17-8
Smiles
C[C@@]12[C@@]3 ([C@@] (C) (OC=4C (=C3) C=C (O) C (=O) C4) CC[C@]1 (C (C) (C) CCC2) [H]) [H]
Molecular Formula
C21H28O3
Molecular Weight
328.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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