FAK-IN-7

FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 μM) . FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].

Product Specifications

CAS Number

[19948-85-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

FAK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fak-in-7.html

Concentration

10mM

Purity

98.55

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=NN=C(C2=CC=C(C)C=C2)S1)C3=CC=CC=C3

Molecular Formula

C16H13N3OS

Molecular Weight

295.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20 (9) :2789-95.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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