FAK-IN-7
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 μM) . FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].
Product Specifications
CAS Number
[19948-85-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-in-7.html
Concentration
10mM
Purity
98.55
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NN=C(C2=CC=C(C)C=C2)S1)C3=CC=CC=C3
Molecular Formula
C16H13N3OS
Molecular Weight
295.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20 (9) :2789-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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