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Cornigerine

Cornigerine is a colchicine analog derived from Colchicum cornigerum that acts as a potent tubulin polymerization inhibitor. It competitively binds to the colchicine site on tubulin, stimulating GTP hydrolysis. This small molecule is a valuable research tool for studying cytoskeleton dynamics, mitosis, and mechanisms of antimitotic agents in both cellular and biochemical assays.

Product Specifications

CAS Number

6877-25-4

Smiles

O (C) C1=C2C=3C ([C@@H] (NC (C) =O) CCC2=CC4=C1OCO4) =CC (=O) C (OC) =CC3

Molecular Formula

C21H21NO6

Molecular Weight

383.39

Storage Conditions

-20°C

Notes

For research use only.

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