E7974
E7974 is a synthetic hemiasterlin analog that acts as a potent antimitotic agent by binding to the Vinca site on tubulin, inhibiting polymerization and disrupting microtubule dynamics. It demonstrates preferential affinity for the βIII-tubulin isotype and has shown antitumor activity in preclinical in vivo models, supporting its investigation in cancer research.
Product Specifications
CAS Number
610787-07-0
Smiles
C (N[C@H] (C (N ([C@H] (/C=C (/C (O) =O) \C) [C@@H] (C) C) C) =O) C (C) (C) C) (=O) [C@@H]1N (C (C) C) CCCC1
Molecular Formula
C24H43N3O4
Molecular Weight
437.62
Storage Conditions
-20°C
Notes
For research use only.
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