Cirazoline (free base)

Cirazoline is a small molecule adrenergic receptor ligand with a unique pharmacological profile. It acts as a full α1A agonist, a partial agonist at α1B and α1D subtypes, and a non-selective α2 antagonist. This profile underpins its utility in vascular research, particularly for studying vasoconstriction mechanisms in both in vitro and in vivo experimental models.