KRH-1636
KRH-1636 is a highly potent and selective oral CXCR4 antagonist that blocks X4-tropic HIV-1 entry and replication in vitro by inhibiting viral fusion and SDF-1α signaling. Its research applications include studying HIV pathogenesis, coreceptor tropism, and CXCR4-mediated cell migration in both cellular and animal models of infection and metastasis.
Product Specifications
CAS Number
568526-77-2
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
[C@H] (NC ([C@@H] (NC (=O) C1=CC=C (CNCC2=CC=CC=N2) C=C1) CCCNC (=N) N) =O) (C) C=3C4=C (C=CC3) C=CC=C4
Molecular Formula
C32H37N7O2
Molecular Weight
551.68
Storage Conditions
-20°C
Notes
For research use only.
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