Methotrexate di-n-butyl ester
Methotrexate di-n-butyl ester is a cell-permeable prodrug of methotrexate, functioning as an antimetabolite and immunosuppressant by inhibiting dihydrofolate reductase. This blockade of tetrahydrofolate synthesis impairs DNA replication, making it a tool for studying anticancer and immunosuppressive mechanisms in both cellular and animal models.
Product Specifications
CAS Number
50602-77-2
Field of Research
Pharmacology & Drug Discovery
Smiles
NC=1C2=C (N=CC (CN (C) C3=CC=C (C (N[C@@H] (CCC (OCCCC) =O) C (OCCCC) =O) =O) C=C3) =N2) N=C (N) N1
Molecular Formula
C28H38N8O5
Molecular Weight
566.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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