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SN-28049

SN-28049 is a GC-selective DNA intercalator with a multifaceted mechanism involving topo IIα poisoning, topo I suppression, and SP-1-mediated transcriptional inhibition. Its promising in vivo activity against murine Colon 38 adenocarcinoma supports its investigation as an experimental anticancer agent for solid tumors in both cellular and animal models.

Product Specifications

CAS Number

492472-30-7

Smiles

C (NCCN (C) C) (=O) C=1C=2C (=CC3=C (N2) C (C) =CC=C3) C (=O) N (C) C1

Molecular Formula

C19H22N4O2

Molecular Weight

338.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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