SN-28049
SN-28049 is a GC-selective DNA intercalator with a multifaceted mechanism involving topo IIα poisoning, topo I suppression, and SP-1-mediated transcriptional inhibition. Its promising in vivo activity against murine Colon 38 adenocarcinoma supports its investigation as an experimental anticancer agent for solid tumors in both cellular and animal models.
Product Specifications
CAS Number
492472-30-7
Smiles
C (NCCN (C) C) (=O) C=1C=2C (=CC3=C (N2) C (C) =CC=C3) C (=O) N (C) C1
Molecular Formula
C19H22N4O2
Molecular Weight
338.4
Storage Conditions
-20°C
Notes
For research use only.
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