CGP74514A
CGP74514A is a selective CDK1 inhibitor that induces apoptosis in cancer cells like U937 through caspase activation and mitochondrial events, which can be blocked by Bcl-2 family proteins. It also triggers cell cycle alterations, including p21 upregulation and pRb dephosphorylation. This compound is a valuable research tool for studying cell cycle regulation and apoptosis mechanisms in vitro.
Product Specifications
CAS Number
481724-82-7
Field of Research
Cell Biology
Purity
99.18% (May vary between batches)
Smiles
N (C1=C2C (N (CC) C=N2) =NC (N[C@@H]3[C@H] (N) CCCC3) =N1) C4=CC (Cl) =CC=C4.Cl
Molecular Formula
C19H25Cl2N7
Molecular Weight
422.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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