GGTI-2166
GGTI-2166 is a selective geranylgeranyl transferase I (GGTase I) inhibitor that blocks RANKL- and TNF-α-induced osteoclastogenesis and TRAP activity in murine MD and RAW 264.7 cells. It prevents protein geranylgeranylation, making it a valuable research tool for studying bone resorption, inflammation, and Ras-related signaling pathways in vitro.
Product Specifications
CAS Number
478908-51-9
Smiles
C (N[C@H] (C (OC) =O) CC (C) C) (=O) C1=C (C=C (NCC2=CN=CN2) C=C1) C3=C (C) C=CC=C3
Molecular Formula
C25H30N4O3
Molecular Weight
434.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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