AZD-1236
AZD1236 is a selective, potent inhibitor of human MMP-9 and MMP-12, demonstrating significant anti-inflammatory effects in preclinical models of lung injury. It has been shown to reduce hemorrhage and macrophage infiltration in rodent models of tobacco smoke exposure and MMP-12 instillation, supporting its research application in studying chronic obstructive pulmonary disease (COPD) and acute lung injury pathways.
Product Specifications
CAS Number
459814-89-2
Field of Research
Protein Biochemistry
Smiles
S (C[C@@]1 (C) NC (=O) NC1=O) (=O) (=O) N2CCC (OC3=CC=C (Cl) C=N3) CC2
Molecular Formula
C15H19ClN4O5S
Molecular Weight
402.85
Storage Conditions
-20°C
Notes
For research use only.
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