2,2,2-Trichloroethanol
2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4) [1].
Product Specifications
CAS Number
[115-20-8]
UNSPSC
12352211
Hazard Statement
H302, H318, H336
Target
Endogenous Metabolite; Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-2-2-trichloroethanol.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(Cl)(Cl)CO
Molecular Formula
C2H3Cl3O
Molecular Weight
149.40
Precautions
H302, H318, H336
References & Citations
[1]Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332 (3) :803-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1367113-01 0.02 mg (E-Coli)
Recombinant Yersinia pestis bv. Antiqua Phosphoribosylaminoimidazole-succinocarboxamide synthase (purC)
Ask
View Details