CEP-7055
CEP-18770 is an orally active proteasome inhibitor with antineoplastic potential. It blocks NF-κB signaling by stabilizing IκBα, leading to apoptosis in tumor cells, and demonstrates a favorable cytotoxicity profile compared to bortezomib in vitro. This agent is used in cancer research, particularly for studying multiple myeloma and solid tumor models in preclinical studies.
Product Specifications
CAS Number
402857-58-3
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (CCOC (CN (C) C) =O) N1C=2C (=C3C (=C4C2CC=5C4=CC=CC5) C (=O) NC3) C=6C1=CC=C (COC (C) C) C6
Molecular Formula
C32H35N3O4
Molecular Weight
525.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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