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NH2-c[X-R-L-S-X]-K-G-P- (D-1Nal)

Selected Variant

GTR19220022-01

Size: 5 mg

Compound 39 is a potent and balanced APJ receptor agonist with sub-nanomolar binding affinity (Ki = 0.6 nM) . It effectively activates Gαi1 signaling (EC50 = 0.8 nM) and recruits β-arrestin2 (EC50 = 31 nM), making it a valuable tool for studying APJ receptor pharmacology in cardiovascular research, both in vitro and in vivo.

Product Specifications

CAS Number

2891469-80-8

Field of Research

Pharmacology & Drug Discovery

Molecular Formula

C49H73N13O11

Molecular Weight

1020.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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