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RORγt inverse agonist 14

The potent and selective RORγt inverse agonist 14 (8e) demonstrates oral activity with an EC50 of 2.5 nM. It is a valuable research tool for investigating Th17-driven pathologies, showing anti-inflammatory effects in both cellular assays and in vivo models of rheumatoid arthritis and psoriasis.

Product Specifications

CAS Number

2672496-70-5

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C26H26F8N2O6S2

Molecular Weight

678.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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