RORγt inverse agonist 14
The potent and selective RORγt inverse agonist 14 (8e) demonstrates oral activity with an EC50 of 2.5 nM. It is a valuable research tool for investigating Th17-driven pathologies, showing anti-inflammatory effects in both cellular assays and in vivo models of rheumatoid arthritis and psoriasis.
Product Specifications
CAS Number
2672496-70-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C26H26F8N2O6S2
Molecular Weight
678.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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