Lepadin H
Lepadin H is a marine-derived alkaloid that induces ferroptosis by activating the p53 pathway, leading to SLC7A11/GPX4 downregulation and ACSL4 upregulation. This mechanism increases ROS and lipid peroxidation, making it a valuable tool for studying ferroptosis in cancer research models, both in vitro and in vivo.
Product Specifications
CAS Number
412328-25-7
Field of Research
Cell Biology
Smiles
C (CCC[C@@H] (CCC) O) [C@@H]1[C@]2 ([C@] (N[C@@H] (C) [C@H] (OC (/C=C/C=C/CCC) =O) C2) (CCC1) [H]) [H]
Molecular Formula
C26H45NO3
Molecular Weight
419.64
Storage Conditions
-20°C
Notes
For research use only.
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