Keap1-Nrf2-IN-10
Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer that effectively reduces oxidative stress. In gamma-irradiated mice, it lowers hepatic MDA, ROS, and NQO1 levels, leading to an increased survival rate. This small molecule is a valuable research tool for studying the Nrf2 pathway in models of oxidative damage and radioprotection.
Product Specifications
CAS Number
2445349-54-0
Field of Research
Cancer Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
O=C1C=2C=C (I) C=C (I) C2N=C (SCC (=O) NC3=CC (OC) =C (OC) C (OC) =C3) N1C4=CC=C (C=C4) S (=O) (=O) N
Molecular Formula
C25H22I2N4O7S2
Molecular Weight
808.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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