ICMT-IN-54
ICMT-IN-54 (compound 7c) is a 12.4 μM inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrated by its inhibition of BFC substrate methylation in yeast. This adamantyl-based compound is a useful chemical probe for studying protein prenylation and methylation in cancer and cardiovascular research, applicable in both in vitro and cellular assays.
Product Specifications
CAS Number
908856-14-4
Field of Research
Cell Biology, Metabolism Research
Smiles
C (N[C@@H] (CSC/C=C (/CC/C=C (/CCC=C (C) C) \C) \C) C (O) =O) (=O) C12CC3CC (C1) CC (C2) C3
Molecular Formula
C29H45NO3S
Molecular Weight
487.74
Storage Conditions
-20°C
Notes
For research use only.
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