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GTPγS tetralithium

GTPγS tetralithium is a non-hydrolyzable GTP analog that activates G-proteins and stabilizes proteins against degradation. It is widely used in vitro and ex vivo to study GPCR signaling, including receptor activation and desensitization assays, for both recombinant and endogenous receptor systems.

Product Specifications

CAS Number

94825-44-2

Product Name Alternative

Guanosine 5'-[γ-thio]triphosphate tetralithium

Field of Research

Metabolism Research

Purity

75.00% (May vary between batches)

Solubility

H2O:80 mg/mL (142.1 mM)

Smiles

O[C@H]1[C@@H] (O[C@@H] ([C@H]1O) COP (OP (OP ([O-]) ([S-]) =O) ([O-]) =O) ([O-]) =O) N2C3=C (C (N=C (N3) N) =O) N=C2.[Li+].[Li+].[Li+].[Li+]

Molecular Formula

C10H12Li4N5O13P3S

Molecular Weight

562.98

Storage Conditions

-20°C

Notes

For research use only.

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