GTPγS tetralithium
GTPγS tetralithium is a non-hydrolyzable GTP analog that activates G-proteins and stabilizes proteins against degradation. It is widely used in vitro and ex vivo to study GPCR signaling, including receptor activation and desensitization assays, for both recombinant and endogenous receptor systems.
Product Specifications
CAS Number
94825-44-2
Product Name Alternative
Guanosine 5'-[γ-thio]triphosphate tetralithium
Field of Research
Metabolism Research
Purity
75.00% (May vary between batches)
Solubility
H2O:80 mg/mL (142.1 mM)
Smiles
O[C@H]1[C@@H] (O[C@@H] ([C@H]1O) COP (OP (OP ([O-]) ([S-]) =O) ([O-]) =O) ([O-]) =O) N2C3=C (C (N=C (N3) N) =O) N=C2.[Li+].[Li+].[Li+].[Li+]
Molecular Formula
C10H12Li4N5O13P3S
Molecular Weight
562.98
Storage Conditions
-20°C
Notes
For research use only.
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