GPI-1046
GPI-1046 is a non-immunosuppressive ligand of the immunophilin FKBP12; induces ARNT expression with subsequent activation of ALK3-dependent canonical BMP signaling responses and attenuates chronic organ failure in models of chronic kidney, but also cardiac and liver injuries; reduces ethanol consumption in part through activation of GLT1 in alcohol-preferring rats.Parkinson Disease Discontinued.
Product Specifications
CAS Number
186452-09-5
Product Name Alternative
GPI1046 | GPI 1046
Field of Research
Metabolism Research
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (277.43 mM)
Smiles
CCC (C) (C) C (=O) C (=O) N1CCCC1C (=O) OCCCC2=CN=CC=C2
Molecular Formula
C20H28N2O4
Molecular Weight
360.454
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- (3-pyridyl) -1-propyl (2S) -1- (3,3-dimethyl-1,2-dioxopentyl) -2-pyrrolidinecarboxylate
Available Sizes
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