Nirmatrelvir
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . (In Vitro) :PF-07321332 is a promising oral antiviral clinical candidate with well-established anti-SARS-CoV-2 activity in vitro. (In Vitro) :3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.1. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.
Product Specifications
CAS Number
2628280-40-8
Product Name Alternative
PF-07321332
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 140 mg/mL (280.26 mM)
Smiles
CC (C) (C) [C@@H] (C (N (C[C@@H]1C (C) (C) [C@H]11) [C@@H]1C (N[C@@H] (C[C@H] (CCN1) C1=O) C#N) =O) =O) NC (C (F) (F) F) =O
Molecular Formula
C23H32F3N5O4
Molecular Weight
499.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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